Additional or alternative non-surgical cancer treatments

TAE, transarterial embolization

TACE, transarterial chemoembolization

TARE,transarterial radioembolization

Chemsat., Chemosaturation,

AVAS-LIOX ,Izolated liver perfusion with oxaliplatin

What is transarterial embolization (TAE)?

Transarterial embolization (TAE) is a minimally invasive procedure that involves the injection of tiny particles or substances into the blood vessels that supply blood to a tumor or other medical condition. The particles or substances are used to block the blood vessels, which can help to shrink the tumor or stop bleeding.

What types of conditions can be treated with transarterial embolization (TAE)?

Transarterial embolization (TAE) can be used to treat a variety of medical conditions, including liver cancer, kidney cancer, lung cancer, uterine fibroids, and vascular malformations. It may also be used to control bleeding caused by trauma, injury, or surgery.

How is transarterial embolization (TAE) performed?

Transarterial embolization (TAE) is performed by an interventional radiologist, who will insert a catheter into a blood vessel in your groin or arm and guide it to the blood vessel that supplies blood to the tumor or medical condition. Tiny particles or substances are then injected into the blood vessel to block it and prevent blood flow to the tumor or medical condition.

Is transarterial embolization (TAE) painful?

Transarterial embolization (TAE) is usually performed under local anesthesia, which means that you will be awake but numb during the procedure. You may feel some discomfort or pressure during the procedure, but it should not be painful.

What are the risks and complications of transarterial embolization (TAE)?

Like any medical procedure, transarterial embolization (TAE) carries some risks and potential complications. These can include bleeding, infection, damage to nearby organs or blood vessels, and allergic reactions to the substances used in the procedure.

What is the recovery like after transarterial embolization (TAE)?

After transarterial embolization (TAE), you will typically need to stay in the hospital for a few days for observation and monitoring. You may experience some mild pain or discomfort at the site of the catheter insertion, but this can usually be managed with over-the-counter pain medications. You will need to avoid strenuous activity for a few days after the procedure.

How effective is transarterial embolization (TAE)?

Transarterial embolization (TAE) can be an effective treatment for certain types of medical conditions. The effectiveness of the procedure will depend on the specific condition being treated and the individual patient's health and circumstances. Your doctor can provide you with more information about the expected outcomes of the procedure in your particular case.

Are there any alternatives to transarterial embolization (TAE)?

Depending on the specific medical condition being treated, there may be alternative treatments available to transarterial embolization (TAE). These can include surgery, radiation therapy, or other minimally invasive procedures. Your doctor can discuss the various treatment options with you and help you determine which approach is best for your particular situation.

How long does the transarterial embolization (TAE) procedure take?

The length of the transarterial embolization (TAE) procedure can vary depending on the specific medical condition being treated and the complexity of the procedure. In general, the procedure can take anywhere from 1-3 hours.

How long does it take to see the results of transarterial embolization (TAE)?

The time it takes to see the results of transarterial embolization (TAE) can vary depending on the specific medical condition being treated. In some cases, you may start to see improvements within a few days of the procedure. In other cases, it may take several weeks or months to see the full effects of the treatment.

Are there any side effects of transarterial embolization (TAE)?

While transarterial embolization (TAE) is generally considered safe, there can be some side effects associated with the procedure. These can include pain or discomfort at the site of the catheter insertion, nausea, vomiting, and fever. Your doctor can provide you with more information about the potential side effects of the procedure and how to manage them.

How often can transarterial embolization (TAE) be repeated?

The frequency with which transarterial embolization (TAE) can be repeated will depend on the specific medical condition being treated and the individual patient's health and circumstances. In some cases, the procedure may be repeated multiple times over a period of weeks or months. Your doctor can provide you with more information about the recommended frequency of the procedure in your particular case.

Will I need to undergo any special preparation before the transarterial embolization (TAE) procedure?

You may need to undergo some special preparation before the transarterial embolization (TAE) procedure, such as fasting for a certain amount of time before the procedure or stopping certain medications. Your doctor will provide you with specific instructions on how to prepare for the procedure.

What should I expect during the recovery period after transarterial embolization (TAE)?

During the recovery period after transarterial embolization (TAE), you may need to take it easy for a few days or weeks. You may experience some mild pain or discomfort at the site of the catheter insertion, which can usually be managed with over-the-counter pain medications. Your doctor will provide you with specific instructions on how to care for yourself during the recovery period.

What is postembolization syndrome?

Postembolization syndrome is a group of symptoms that some patients may experience after undergoing transarterial embolization (TAE) or another type of embolization procedure. These symptoms can include pain, fever, nausea, vomiting, and fatigue. Postembolization syndrome is thought to occur as a result of the body's response to the embolization material that has been injected into the blood vessels to block the blood supply to a tumor or other abnormal tissue. The embolization material causes an inflammatory reaction in the surrounding tissues, which can lead to the symptoms of postembolization syndrome. Postembolization syndrome is usually self-limiting and resolves on its own within a few days to a week after the procedure. Your doctor may recommend over-the-counter pain relievers or prescribe medications to help manage the symptoms. In rare cases, more serious complications may occur, such as infection or bleeding, and these should be reported to your doctor immediately.

What is indications of TAE for oncologic or cancer  patients?

Transarterial embolization (TAE) can be used as a treatment option for a variety of oncologic conditions. Some of the specific indications of TAE for oncologic patients include:

Hepatocellular carcinoma (HCC): TAE can be used to treat HCC, which is the most common type of liver cancer. TAE can help to reduce the size of the tumor and block the blood supply to the cancer cells, which can help to slow or stop the growth of the tumor.

Metastatic liver cancer: TAE can also be used to treat liver cancer that has spread to the liver from another part of the body. By blocking the blood supply to the tumors in the liver, TAE can help to slow the growth of the cancer and improve symptoms.

Neuroendocrine tumors: TAE can be used to treat neuroendocrine tumors, which are rare tumors that can occur in various parts of the body, including the pancreas, lungs, and gastrointestinal tract.

Renal cell carcinoma: TAE can be used to treat renal cell carcinoma, which is a type of kidney cancer. TAE can help to reduce the size of the tumor and block the blood supply to the cancer cells, which can help to slow or stop the growth of the tumor.

Lung cancer: TAE can be used to treat lung cancer that has spread to the liver, as well as primary lung tumors that cannot be treated with surgery or radiation.

The specific indication for TAE will depend on the type and stage of the cancer, as well as the patient's overall health and medical history. Your doctor can help you determine if TAE is the right treatment option for your particular situation.

What is transarterial chemoembolization?

Transarterial chemoembolization (TACE) is a procedure used to treat cancer in the liver. It involves injecting chemotherapy drugs directly into the blood vessels that supply the tumor, followed by the injection of particles that block the flow of blood to the tumor. This causes the tumor to be deprived of oxygen and nutrients, ultimately resulting in its destruction.

What types of cancer can be treated with TACE?

TACE is primarily used to treat liver cancer, particularly hepatocellular carcinoma (HCC). It may also be used to treat metastatic cancer that has spread to the liver from other parts of the body, such as colorectal cancer.

How is TACE performed?

TACE is performed using a catheter, which is a thin, flexible tube that is inserted through a small incision in the groin and guided to the blood vessels in the liver using X-ray guidance. Once the catheter is in place, chemotherapy drugs are injected directly into the blood vessels that supply the tumor. This is followed by the injection of particles that block the flow of blood to the tumor.

What are the benefits of TACE?

TACE can be an effective treatment option for patients with liver cancer, particularly those who are not candidates for surgery or liver transplantation. It can help to shrink tumors, relieve symptoms such as pain and discomfort, and improve overall quality of life. TACE can also be repeated if necessary, making it a potentially long-term treatment option.

What are the risks of TACE?

Like any medical procedure, TACE does carry some risks. The most common side effects include pain or discomfort at the site of the catheter insertion, fever, and nausea. In rare cases, more serious complications such as bleeding, infection, or liver damage may occur.

How long does the TACE procedure take?

The length of the TACE procedure can vary depending on the size and location of the tumor, as well as other factors such as the patient's overall health. In general, the procedure takes a few hours to complete, including preparation and recovery time.

How long does it take to recover from TACE?

Recovery time can vary depending on the patient's individual circumstances, but most patients can expect to spend a night in the hospital following the procedure. They may experience some pain or discomfort for a few days, but can usually return to normal activities within a week or two.

What should I expect after TACE?

Following TACE, patients will have regular follow-up appointments with their healthcare provider to monitor their progress and assess the effectiveness of the treatment. They may also undergo additional imaging tests, such as CT or MRI scans, to evaluate the size and location of the tumor.

Are there any alternatives to TACE?

There are several other treatment options available for liver cancer, including surgery, radiation therapy, and other types of targeted therapy. The best treatment option will depend on the individual patient's circumstances and the stage of their cancer. It is important to discuss all options with a healthcare provider to determine the most appropriate course of treatment.

Is TACE a cure for liver cancer?

TACE is not a cure for liver cancer, but it can be an effective treatment option that can help to slow the progression of the disease and improve quality of life. It is often used in combination with other treatments, such as surgery or radiation therapy.

Can TACE be used to treat cancer that has spread beyond the liver?

TACE is primarily used to treat liver cancer, but it may also be used to treat cancer that has spread to other parts of the body. However, its effectiveness in these cases may be limited.

How many TACE treatments will I need?

The number of TACE treatments required will depend on the size and location of the tumor, as well as other factors such as the patient's overall health. Most patients require multiple treatments spaced several weeks or months apart.

Is TACE a painful procedure?

TACE is generally well-tolerated, but patients may experience some pain or discomfort during the procedure and in the days following. Pain management strategies, such as medication or local anesthesia, may be used to minimize discomfort.

Can I drive home after the TACE procedure?

Patients should not drive or operate heavy machinery for at least 24 hours following the TACE procedure. They should arrange for someone to drive them home from the hospital.

Can I eat and drink normally after TACE?

Patients may need to follow specific dietary restrictions following the TACE procedure, such as avoiding alcohol or limiting certain types of food. Your healthcare provider will provide specific instructions regarding diet and other post-procedure care.

What are the types of TACE?

There are several different types of transarterial chemoembolization (TACE) that may be used to treat liver cancer. These include:

Conventional TACE: This is the most common type of TACE and involves the injection of chemotherapy drugs followed by the injection of small particles or beads that block the blood vessels supplying the tumor.

Drug-eluting bead TACE (DEB-TACE): This type of TACE uses small beads or particles that are coated with chemotherapy drugs. The beads are injected directly into the blood vessels supplying the tumor, where they slowly release the drugs over time.

Radioembolization (Y-90): This is a type of TACE that uses tiny radioactive particles that are injected into the blood vessels supplying the tumor. The radiation helps to kill the cancer cells.

Transarterial oily chemoembolization (TOCE): This type of TACE uses an oily substance to carry the chemotherapy drugs to the tumor. The oily substance also blocks the blood vessels supplying the tumor.

Transarterial embolization (TAE): This is a type of TACE that involves the injection of small particles or beads that block the blood vessels supplying the tumor. Unlike conventional TACE, it does not involve the injection of chemotherapy drugs.

The specific type of TACE used will depend on the individual patient's circumstances, the size and location of the tumor, and other factors such as overall health and medical history.

What are indications of TACE?

Transarterial chemoembolization (TACE) is a minimally invasive procedure that is primarily used to treat primary liver cancer (hepatocellular carcinoma). TACE may also be used to treat other types of cancer that have spread to the liver.

The following are the indications for TACE:

Liver cancer that has not spread beyond the liver: TACE is most commonly used to treat liver cancer that is localized to the liver and has not spread to other parts of the body.

Tumor size and number: TACE is typically used to treat tumors that are too large to be treated with surgery, or when surgery is not an option due to the location of the tumor or other medical factors. TACE may also be used to treat multiple tumors in the liver.

Liver function: TACE may be recommended for patients with liver cancer who have good liver function, meaning that their liver is functioning well enough to tolerate the procedure.

Unresectable tumors: TACE may be recommended for patients with unresectable tumors, meaning that the tumor cannot be completely removed with surgery.

Palliative care: TACE may be used as a palliative treatment to help relieve symptoms and improve quality of life in patients with advanced liver cancer.

Your healthcare provider will determine if TACE is a suitable treatment option for you based on various factors, including the stage and location of your cancer, your overall health and medical history, and your personal preferences.

What are risks and complications of TACE ?

Transarterial chemoembolization (TACE) is generally a safe procedure, but like any medical procedure, it does carry some risks and potential complications. The risks and complications of TACE can vary depending on various factors such as the patient's overall health, the size and location of the tumor, and the specific type of TACE used. The following are some possible risks and complications of TACE:

Pain or discomfort: Patients may experience some pain or discomfort during the procedure and in the days following. Pain management strategies, such as medication or local anesthesia, may be used to minimize discomfort.

Nausea and vomiting: Some patients may experience nausea and vomiting following the procedure.

Liver damage: TACE may cause damage to healthy liver tissue, which can lead to liver failure in rare cases.

Bleeding: TACE may cause bleeding in the liver or other parts of the body. In rare cases, this can be serious and require additional treatment or hospitalization.

Infection: There is a small risk of infection following TACE, particularly if the patient has a weakened immune system.

Allergic reactions: Patients may have an allergic reaction to the contrast dye or other medications used during the procedure.

Kidney damage: TACE may cause damage to the kidneys, particularly in patients with pre-existing kidney problems.

Radiation exposure: Some types of TACE, such as radioembolization, involve exposure to radiation, which can increase the risk of certain cancers or other health problems.

It is important to discuss the potential risks and complications of TACE with your healthcare provider before the procedure. Your healthcare provider can provide guidance on how to minimize these risks and can monitor you closely for any potential complications following the procedure.

Which chemotherapy drugs could be used for TACE ?

Several different chemotherapy drugs may be used for transarterial chemoembolization (TACE) to treat liver cancer. The specific drugs used will depend on various factors, including the size and location of the tumor, the patient's overall health, and the type of TACE being performed. The following are some of the chemotherapy drugs commonly used for TACE:

Doxorubicin: Doxorubicin is a type of chemotherapy drug that is commonly used for TACE. It is usually injected directly into the blood vessels supplying the tumor during the procedure.

Cisplatin: Cisplatin is another chemotherapy drug that may be used for TACE. It is usually injected directly into the blood vessels supplying the tumor during the procedure.

Mitomycin-C: Mitomycin-C is a chemotherapy drug that may be used alone or in combination with other drugs for TACE.

Epirubicin: Epirubicin is a chemotherapy drug that may be used alone or in combination with other drugs for TACE.

Irinotecan: Irinotecan is a chemotherapy drug that may be used alone or in combination with other drugs for TACE.

The chemotherapy drugs used for TACE are often mixed with contrast dye and other substances to help target the tumor and improve the effectiveness of the treatment. The specific combination of drugs and other substances used will depend on the patient's individual circumstances and the recommendations of their healthcare provider.

Is TARE superior to TACE?

The question of whether transarterial radioembolization (TARE) is superior to transarterial chemoembolization (TACE) for the treatment of liver cancer is a matter of ongoing debate among healthcare professionals. Both TARE and TACE have been shown to be effective treatments for liver cancer, but they differ in some ways that may make one treatment more suitable for certain patients than the other.

TARE involves the injection of tiny beads containing radioactive particles directly into the blood vessels supplying the tumor. The radiation then destroys the cancer cells over time. TACE involves the injection of chemotherapy drugs directly into the blood vessels supplying the tumor, followed by the injection of substances that block the blood flow to the tumor, thereby trapping the chemotherapy drugs inside the tumor and maximizing their effectiveness.

Studies have shown that both TARE and TACE can be effective treatments for liver cancer, but TARE may be more effective for certain types of tumors or for patients who are not suitable candidates for TACE. For example, TARE may be more effective for tumors that are located in difficult-to-reach areas of the liver, or for tumors that are too large or too advanced to be treated with TACE. Additionally, TARE may be less likely to cause damage to healthy liver tissue than TACE.

However, TARE is a more complex and expensive procedure than TACE, and it is not suitable for all patients. TARE requires specialized equipment and training, and patients must be carefully selected to ensure that they are suitable candidates for the procedure. In some cases, TARE may be associated with a higher risk of complications than TACE, such as radiation-induced liver disease or other radiation-related side effects.

In summary, the choice between TARE and TACE for the treatment of liver cancer will depend on various factors, including the patient's individual circumstances and the recommendations of their healthcare provider. Both treatments have been shown to be effective for liver cancer, but the most suitable treatment will depend on the specific characteristics of the tumor and the patient's overall health.

What is transarterial radioembolization (TARE)?

Transarterial radioembolization (TARE) is a minimally invasive procedure used to treat liver cancer. It involves the use of tiny radioactive beads that are delivered directly to the tumor via the hepatic artery. These beads are usually made of a material called yttrium-90 (Y-90), which emits radiation that can destroy cancer cells.

During the procedure, a catheter is inserted into an artery in the groin and guided through the blood vessels to the hepatic artery that supplies blood to the liver. Once the catheter is in place, the radioactive beads are injected through it and travel to the tumor site. The beads get lodged in the small blood vessels surrounding the tumor, where they emit radiation and destroy the cancer cells.

TARE is an effective treatment option for liver cancer, particularly for patients who are not eligible for surgery or other forms of treatment. The procedure can be performed on an outpatient basis, and patients usually experience minimal side effects. However, TARE is not suitable for all types of liver cancer, and it is important to consult with a medical professional to determine if this treatment is appropriate for a particular case.

Who is a candidate for TARE?

TARE may be a suitable treatment option for patients with liver cancer that cannot be treated with surgery, such as those with advanced-stage disease or those who are not candidates for other treatments. Patients who have tumors that are too large or too advanced for transarterial chemoembolization (TACE) may also be suitable candidates for TARE.

How is TARE performed?

During TARE, a catheter is inserted through a small incision in the groin and threaded up to the blood vessels that supply the liver. Tiny beads containing radioactive particles are then injected through the catheter and into the blood vessels supplying the tumor. The radioactive particles then destroy the cancer cells over time.

What are the benefits of TARE?

TARE has several benefits for patients with liver cancer. It is a minimally invasive procedure that is associated with fewer side effects than other treatments, such as chemotherapy. TARE may also be more effective than other treatments for certain types of liver cancer, and it may be associated with a longer period of disease control.

What are the risks and side effects of TARE?

Like all medical procedures, TARE has some risks and potential side effects. The most common side effects of TARE include fatigue, nausea, and abdominal pain. Some patients may also experience an increase in liver enzymes, which usually resolves on its own. More serious side effects, such as radiation-induced liver disease or other radiation-related side effects, are rare but can occur.

How long does it take to recover from TARE?

Recovery from TARE is usually fairly quick. Most patients are able to go home on the same day as the procedure, and they can typically return to normal activities within a few days to a week. Patients may need to take pain medications or other medications to manage any side effects they experience after the procedure.

Is TARE a curative treatment for liver cancer?

TARE is not a curative treatment for liver cancer, but it can be an effective treatment for managing the disease and improving quality of life. The goal of TARE is to shrink the tumor and slow the progression of the disease, but it may not eliminate the cancer completely. In some cases, TARE may be used in combination with other treatments, such as chemotherapy or surgery, to achieve the best possible outcome for the patient.

Is TARE painful?

Patients may experience some discomfort during and after the TARE procedure, but they should not experience significant pain. Patients are usually given a local anesthetic to numb the area where the catheter is inserted, and they may be given sedation to help them relax during the procedure.

How long does the TARE procedure take?

The TARE procedure usually takes between 1-2 hours, although this can vary depending on the size and location of the tumor, as well as the patient's individual circumstances. Patients may need to spend several hours in the hospital after the procedure for observation.

Are there any dietary restrictions after TARE?

Patients may be advised to follow a low-fat diet for a period of time after TARE to help reduce the risk of complications. Patients should also avoid alcohol for at least two weeks after the procedure.

How often do patients need to undergo TARE?

The frequency of TARE treatments will depend on the patient's individual circumstances and the stage of their liver cancer. In some cases, a single TARE treatment may be sufficient to control the disease, while in other cases, multiple treatments may be required.

Can TARE be used to treat other types of cancer?

TARE is primarily used to treat liver cancer, but it may also be used to treat other types of cancer that have spread to the liver, such as neuroendocrine tumors or metastatic colorectal cancer.

How effective is TARE compared to other treatments?

The effectiveness of TARE compared to other treatments, such as chemotherapy or surgery, will depend on the individual patient's circumstances and the stage of their liver cancer. TARE has been shown to be effective for certain types of liver cancer and may be more effective than other treatments for certain patients.

How can patients prepare for TARE?

Patients will typically receive instructions from their healthcare provider on how to prepare for the TARE procedure. This may include fasting for a period of time before the procedure, stopping certain medications, and arranging for transportation to and from the hospital. Patients should also inform their healthcare provider if they have any allergies or other medical conditions that may affect the procedure.

What is chemosaturation (chemosat) treatment?

Chemosaturation (chemosat) treatment is a technique that delivers high doses of chemotherapy drugs directly to the liver while minimizing the exposure of other organs to the drugs. This is achieved by isolating the blood vessels that supply the liver and circulating the chemotherapy drugs through them.

Who is a candidate for chemosaturation treatment?

Chemosaturation treatment may be recommended for patients with liver metastases that cannot be removed surgically and have not responded to other treatments such as chemotherapy.

How is chemosaturation treatment performed?

The procedure is typically performed under general anesthesia. During the procedure, a catheter is inserted into the artery that supplies blood to the liver. The catheter is then used to isolate the blood vessels that supply the liver, and a special device is used to circulate the chemotherapy drugs directly into the liver for approximately 30-60 minutes.

What chemotherapy drugs are used in chemosaturation treatment?

The chemotherapy drugs used in chemosaturation treatment may vary depending on the individual patient's circumstances, but the most commonly used drug is melphalan.

What are the side effects of chemosaturation treatment?

Side effects of chemosaturation treatment may include nausea, vomiting, fatigue, abdominal pain, and fever. These side effects are typically temporary and may be managed with medication.

How long does the recovery process take after chemosaturation treatment?

The recovery process after chemosaturation treatment typically takes several days to a week, and patients may need to stay in the hospital for observation during this time.

How effective is chemosaturation treatment?

The effectiveness of chemosaturation treatment may vary depending on the individual patient's circumstances, but it has been shown to be effective in some patients with liver metastases that have not responded to other treatments.

Are there any risks or complications associated with chemosaturation treatment?

As with any medical procedure, there are risks and potential complications associated with chemosaturation treatment. These may include bleeding, infection, and damage to other organs or tissues. Patients should discuss the risks and benefits of the treatment with their healthcare provider.

How long does the chemosaturation treatment take?

The duration of chemosaturation treatment may vary depending on the size and location of the liver tumors and the individual patient's circumstances. Typically, the procedure takes between 2-4 hours, including preparation and recovery time.

Can chemosaturation treatment be repeated?

Chemosaturation treatment can be repeated if necessary, depending on the individual patient's response to the treatment and the progression of the disease.

Can other treatments be used in combination with chemosaturation treatment?

Other treatments such as radiation therapy, targeted therapy, or immunotherapy may be used in combination with chemosaturation treatment depending on the individual patient's circumstances and the type and stage of their cancer.

Is chemosaturation treatment covered by insurance?

Chemosaturation treatment is a relatively new and specialized treatment and may not be covered by all insurance providers. Patients should check with their healthcare provider and insurance company to determine their coverage and any potential out-of-pocket costs.

How does chemosaturation treatment compare to other treatments for liver cancer?

The effectiveness of chemosaturation treatment compared to other treatments such as surgery, radiation therapy, or systemic chemotherapy may vary depending on the individual patient's circumstances and the type and stage of their cancer. In some cases, chemosaturation treatment may be more effective than other treatments, while in other cases, a combination of treatments may be necessary.

What is the recovery period after chemosaturation treatment?

The recovery period after chemosaturation treatment typically takes several days to a week, during which time patients may experience side effects such as fatigue, nausea, and abdominal pain. Patients should follow their healthcare provider's instructions for post-treatment care and management of side effects.

Are there any long-term side effects of chemosaturation treatment?

The long-term side effects of chemosaturation treatment are not well-known, as the treatment is relatively new. Patients should discuss the potential risks and benefits of the treatment with their healthcare provider.

What is AVAS-LIOX Treatment?

The aim of this treatment is to deliver a very high dose of chemotherapy drug to cancerous cells without damaging other organs of the body. The mission of AVAS is to be implanted in a patient to provide repeatable and easy access to the patient's arteries. This allows clinicians to isolate a cancerous organ from the rest of the body. Once isolated, the clinician can treat that organ with high concentrations of anti-cancer agents, such as chemotherapy. The LIOX technique consists of placing the patient's axillary artery access system, facilitating simultaneous multi-catheter access to the patient's intestinal vascular system. Through the access system, balloon catheters are inserted into the patient's intestinal veins and the balloon is inflated, indirectly preventing portal feeding of the liver. Next, another balloon catheter is routed to the appropriate left/right branch or segmental artery of the hepatic artery for oxaliplatin infusion. On average, patients receive five to six treatments with three catheters for three procedures over a 1-month period.

Isolated Liver Perfusion (ILP) with oxaliplatin, also known as hepatic isolated perfusion with oxaliplatin.

What is ILP with oxaliplatin treatment?

ILP with oxaliplatin treatment is a liver-directed therapy used to treat advanced liver cancer that cannot be removed surgically. This treatment involves isolating the liver and circulating a high dose of chemotherapy drug oxaliplatin into the liver through the hepatic artery. This helps to deliver a high dose of chemotherapy directly to the liver, while minimizing its systemic side effects.

Who is a candidate for ILP with oxaliplatin treatment?

Patients with advanced liver cancer that cannot be removed surgically may be candidates for ILP with oxaliplatin treatment. The decision to use this treatment will depend on the individual patient's circumstances, including the type and stage of their cancer, their overall health, and other factors.

How is ILP with oxaliplatin treatment administered?

ILP with oxaliplatin treatment is a surgical procedure that involves isolating the liver and circulating a high dose of chemotherapy drug oxaliplatin into the liver through the hepatic artery. The procedure may take several hours, and patients typically require a hospital stay.

What are the side effects of ILP with oxaliplatin treatment?

The side effects of ILP with oxaliplatin treatment may vary depending on the individual patient's circumstances and the type and stage of their cancer. Common side effects may include nausea, vomiting, abdominal pain, fatigue, and changes in liver function tests. Patients should discuss potential side effects with their healthcare provider before starting treatment.

How effective is ILP with oxaliplatin treatment?

The effectiveness of ILP with oxaliplatin treatment may vary depending on the individual patient's circumstances and the type and stage of their cancer. Clinical studies have shown promising results in treating advanced liver cancer and improving survival rates.

Can ILP with oxaliplatin treatment be used in combination with other treatments?

ILP with oxaliplatin treatment may be used in combination with other treatments, such as systemic chemotherapy, radiation therapy, or immunotherapy, depending on the individual patient's circumstances and the type and stage of their cancer. Patients should discuss potential treatment options with their healthcare provider.

Is ILP with oxaliplatin treatment covered by insurance?

ILP with oxaliplatin treatment is a specialized and relatively new treatment and may not be covered by all insurance providers. Patients should check with their healthcare provider and insurance company to determine their coverage and any potential out-of-pocket costs.